What does the COVID-19 vaccine have to say?

Pandemic Dec 12, 2020

In the time to time outbreak of fatal diseases, vaccines have emerged as the benefactors to the living society. From limiting drug resistance to controlling the spread of epidemics to protecting every individual, vaccines have been an inseparable part of the world’s immune system. Taking public health into consideration, vaccination is an easier and cost-effective solution than the post-treatment itself.

Being aware of the infectious coronavirus disease, also known as the COVID-19, that spreads by the contact of bodily fluids and causes damage depending on one’s immunity strength. Proper precautions do not guarantee a safe state and the probability to be infected by unforeseen circumstances yet remains unchanged. This newly discovered virus has been a challenging mystery to all the scientists throughout the world, but with tireless efforts and dedication, a new ray of hope has emerged.

Potential vaccines are being studied by numerous health organizations to provide a safe and effective solution to this pandemic. Amongst these, Pfizer Inc and its German partner BioNTech claim their vaccine to be effective by more than 90% in the last-stage trials without any major safety concerns. Following in line, US biotechnology company Moderna and German biopharmaceutical company CureVac have also claimed their vaccine’s effectiveness to be near about 95%.

The big-time news is that by the end of 2020, Pfizer/BioNtech vaccine shall reach within the world, while the next leading member Moderna expects it to do so by the spring. Though there always remains a slight scope for improvement and research, the pandemic could soon see its end.

The similarities of these vaccines are the use of mRNA technology. mRNA is the set of instructions by which cells make all proteins and send them to various parts of the body. Medicines made out of this technology take advantage of normal biological processes to express proteins and create a desired therapeutic effect. This enables the potential treatment of a broad spectrum of diseases, many of which cannot be addressed with current technologies. Though the RNA vaccines have never been approved to use, after the consideration from regulatory agencies around the world, there seem to be possibilities to welcome the vaccines.

By the law of the medicinal world, if a drug has its effect on a situation there are also possible side-effects that need to be considered. Even if the RNA technology is used against COVID-19, the well-tolerated vaccine mostly has mild to moderate side-effects that include fatigue, muscle-pain, joint-pains, and headaches.

Since India is one of the largest vaccine producers, it has not stepped back and is equally motivated to develop a vaccine. The vaccine developed by Bharat Biotech Limited is conducting the phase-three trial. The other vaccine candidates of India come from the Serum Institute of India, Zydus Cadila, Dr. Reddy’s Laboratories, and Biological E.

This article has been written by Pooja Varade for The Paradigm

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